Wednesday, January 5, 2011

Extraction | Drilling For Researchers Of Ancient DNA Teeth Hobbit

Cheryl Jones

The scientists plan to try to extract DNA from "Hobbit" by Flores, noted that the extinction of 1 meter distance relatives of modern humans in Indonesia, after a study suggested that the test method for the study of ancient DNA samples and perhaps thwarted previous efforts.

This year, not the Australian Centre for Ancient DNA (ACAD) in Adelaide, Australia geneticist at the University of A-Flores 18,000 years your teeth that have been excavated from the beam ASR a website in 2009 , Java, Indonesia DNA island of Flores.

Molar has been kept cold and drove as little as possible to avoid contaminating modern DNA. But perhaps few, if any, is the ancient DNA survive the tropical heat and humidity, all of which can be very scattered.

Tony Djubiantono, the National Centre for Archaeology in Jakarta, Indonesia, where the director said that in the teeth, problems in the development of the extraction of DNA samples can be overcome in the past, understand the evolutionary history of H. floresiensis great potential.

If you can extract the DNA sequence compared to the classification of other species, may settle the dispute. For example, Peter Brown, Armidale, Australia, described and named the species in 2004, a paleoanthropologist at the University of thought of New England, its original classification. First, it is a species of humans, but suspected Hobbit "before leaving the ancestors of the evolution of species may belong to different and new people are in Africa.

Difficult

Five years ago, two teams, one of the DPA and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, trying to recover another floresiensis teeth discovered in 2003 in the DNA. Both attempts failed.

Now Chris Adler of the ACAD led to the geneticists, the team found that can not be the standard method of sampling to The Hobbit and the other is responsible for the samples of ancient DNA.

Eagle team - including restoring the original DNA-Flores wanted to take part in a number of researchers - Comparing the world of different samples of 40 engineering samples of human mitochondrial DNA, was 7.500 years old . The results were accepted in the journal Archaeology.

The oldest of genetic research has focused on the teeth within the tooth structure, dentin, but eagle team found that the cement, the root is a rich source of DNA.

The hole is usually in the teeth and bone samples from the technology because it reduces damage to precious samples. But Adler Working Group found that more than 1,000 revolutions per minute (RPM) the default rate of heat by the DNA damage occurred rapidly, resulting in yields of up to 30 times more carbon samples in plains. Reduce the penetration rate of 100 rpm, to mitigate this problem.

Max-Planck team tries to recover from an early sign of tooth dentin Hobbit DNA is not clear what is the rate of penetration. Although researchers have used ACAD drilling, which is also concentrated in the dentin. They will try to focus on its cement.

Very unlikely

Adler said, not already in the DNA, and now needs a new sampling and old specimens. She was surprised that the old - tend to DNA, researchers sample drilling at high speed, because dentists have long known that damage to the patient's teeth. "This is a communication between the two areas have similar things to work independently, the absence of cases," he said.

Matthew Collins, an expert in ancient protein analysis in the United Kingdom is the foundation of the University of York, Adler said: "The team" in the sampling results of valuable fossil "will contribute to minimizing Damage to molecules and can it help us to arrive in time restore sequence information back. "

However, DNA Homo floresiensis winkling the possibility of pessimism, which may be too scattered molecules at high temperature by the excavation.

But scientists believe that the value of their attempts ACAD flowers in your teeth. They have in promoting DNA extracted from a site 6,000 years ago in 2007 succeeded pig teeth.

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