Los más comunes son: sulfuro de hidrógeno, el olor a huevos podridos, escatol mercaptanand de metilo, el olor de los excrementos, muertos, como el olor de los cadáveres, putrescina, que era como el olor de la carroña y isovalerato, el olor de pies sudorosos! SÃ, ja, ja! ?
Sabes exactamente lo que el tribunal de una comida para su perro?
"Si la alerta temprana en la cabeza, que está en los primeros 10 años de ojo seco y un perro bolsa de ingredientes, te das cuenta de que no puede descifrar lo que el alimento, o el grupo", dijo Tracie Hotchner y estudiar la Biblia para los perros: todo lo que su perro quiere saber.
Para enseñar a los dueños de perros, placas de identificación y llegar a entender, de encontrar los mejores ingredientes, y la relación Hotchner, una serie de nuevos alimentos para perros, un sitio llamado el perro en la www. proportions.com la nutrición en la Universidad. "Una buena variedad de nutrientes en la parte superior de la lista de proteÃnas de alta calidad es el cliente más importante en la búsqueda de alimentos", dijo.
El sitio proporciona una lista de la decisión de evaluación, el "mejor" y "bueno" y dijo que "los pobres" en las categorÃas de etiquetado sobre propiedades nutritivas, proteÃnas, carbohidratos, grasas y aceites, y conservantes.
"¿Ves" harina de pollo "es una palabra vaga como comunes" pájaro "Esta ave puede ser un montón de habitaciones misteriosas.
"No" t asumir que sólo porque un alimento de perro es una gran empresa, el alimento contiene ingredientes de alta calidad, por lo que dice.
These high-profile skirmishes are two of the latest examples in the debate to allow in-flight cell phone conversations.
In Europe, the Middle East and Asia, airlines that wire planes for connectivity can install special equipment to allow passengers to use their own cell phones to make and receive calls.
Domestic airlines own about 90 percent of the world's connected planes, but federal regulations still ban the use of in-flight mobile calls.
And while Uncle Sam doesn't outlaw mid-air communications made using Skype or other Voice over Internet Protocol (VoIP) services, every U.S. carrier offering broadband has directed service providers such as Aircell/Gogo and Row 44 to block all voice calls and disable the VoIP function.
The disconnection may get wider.
At the end of 2010, more than 2,000 airplanes were wired for connectivity. "We expect that number to increase by 50 percent this year, to roughly 3,000 planes worldwide," said Amy Cravens, a market analyst for In-Stat.
With more international carriers jumping on the connectivity bandwagon, much of that growth will likely be represented by jets owned by airlines planning to, or already providing, mobile phone service.
And unless something changes in the U.S., some analysts worry the only travelers who will be unreachable by mobile phone will be those flying in U.S. airspace.
Vote: Should cell phone use be allowed on planes?
International travelers chat awayProviders such as OnAir and AeroMobile, and a variety of their equipment partners, have been working with international airlines to install equipment that allows mobile phone calls in addition to other entertainment and communication services. (The European Aviation Safety Agency lifted its ban on in-flight cell phone use in 2007.)
Oman Air, Egypt Air, Libyan Airlines, Qatar Airways and Royal Jordanian are among the airlines that currently offer in-flight voice calls on many of its aircraft. British Airways allows mobile phone use on a single route: an all-business class flight between London and New York. Malaysia Airlines and others are conducting trials before committing to a formal rollout of a mobile phone service.
"Emirates is the airline everyone is watching with regard to passenger acceptance of in-flight calls; and of course, whether the service is commercially viable," said Raymond Kollau, a market and trend analyst for Airlinetrends.com. The carrier operates 90 jets equipped with in-flight connectivity.
"People have been able to use their mobile phones on our planes for about three years now," said Patrick Brannelly, Emirates' vice president for product, publishing, digital and events.
Cell phone users made between 15,000 and 20,000 calls per month from Emirates flights in 2010, Brannelly said. "Each call averaged about two minutes. And during that year we had only one complaint," he said. "Now the complaint we're hearing from passengers is why we don't have the mobile phone service on every aircraft."
But not all international carriers are rushing to provide the service.
Based on feedback from a 2008 test of in-flight mobile phone service, Air France spokesperson Karen Gillo said the airline now considers mobile phone calling "a future option ... [We] don't have any current plans to implement it fleet-wide."
Ryanair offered in-flight mobile calling for a while on 50 aircraft, Kollau said. "However, OnAir, who provided the service, decided to stop the partnership reportedly because of a dispute in revenue sharing."
While Lufthansa recently relaunched its FlyNet onboard Internet system, which could allow voice communication, the airline's research suggests it's not a good idea. "Repeated surveys among our customers show that our passengers value a quiet environment without cell phone usage," said spokesperson Christina Semmel.
Cathay Pacific Airways, though, is determined to offer voice calling to passengers. The airline offers broadband Internet service, and supports BlackBerrys and other smartphones. "When we tested this suite of services with our passengers, all were popular, but voice calling was certainly the most polarized," said Alex McGowan, head of product for the airline. "We recognize that some passengers are against the concept, and we will ensure that their fears around the 'nuisance' factor are not realized."
Calling U.S. carriers Back in the states, the regulatory ban and public debate over in-flight phone calls continues, but opposition may be waning.
In 2005, the Bureau of Transportation Statistics asked about 1,000 households if, barring safety issues, cell phones should be allowed on airplanes. Thirty-nine percent said "definitely" or "probably." Four years later, nearly 48 percent of respondents gave the same answers.
The "Halting Airplane Noise to Give Us Peace" Act of 2008, the so-called Hang-Up Act, was approved by the House Transportation and Infrastructure Committee but never became law. However, parts of that proposal, which sought "to establish prohibitions against voice communications using a mobile communications device on commercial airline flights" could end up in another bill that comes before the new Congress.
Earlier Friday, Ben Ali staged demonstrations against the government in a state of emergency in Tunisia reached the limit.
They have banned public gatherings and authorized security forces in Tunisia, refused to obey orders from any person who opened fire. A dusk to dawn curfew was implemented.
Tunisia, which forced the resignation of Ben Ali, is a police Tuesday night, killing 13 people - in particular, the president said the use of live ammunition against demonstrators at the end.
Tuesday County Board meeting, "said County Sheriff Rick Federer members who work with their phones. Because often standing in the office, patrols and other work-related calls the minutes.
ng Josh, who last week appointed vice president, said his phone has been running around U.S. dollars 300 million, because it was "beyond the number of plan minutes.
But how many county residents as cell phones, at least for people who can call some of the free use of the same company, he said.
As representatives of the phone 24-7, inevitably, get personal calls.
"You can not stop people from calling you, if not" know why you call, "said Tim Fox, the county attorney." If they do, I think, are too lenient a politics ... You must understand. "
The county that I can have a policy, can not be delegated, private telephone calls, continued.
Federer said that the best plan, it is six calls, regardless of the number of deputies discovered cost the county $ 160 per month.
Although the Council has decided that representatives should have a working cell phone, asked Chairman Neal Folstad When should provide an opportunity to stop. In 2007, the Council was approached by a handful of leaders are the departments of personnel in the hope of mobile phones. After approval, distribution, case by case to the Committee new mobile phone bill each employee every month, both personal and business calls are detailed.
"For me it is an important sector, is an entirely different function to other departments," said Commissioner è±å°"éå¤«å °.
Sergeant, vice president and some members of the road has been completed, the county telephone. But the workers of public health, emergency management and social status are concerned, "said Commissioner and Stephanie Miranowski.
"I'm not saying that t ISN" That's what we do, but I am saying is that you're talking about six calls, which will focus a lot more than six phone call "to delay (in other sectors), "he said.
Ng Council agreed to the decision of the government's plan to offer cell phone in several counties of staff for more information to work to maintain.
Por lo tanto, "Nuestra sensación es tomar una mayor apertura y comunicación", dijo Sheila Rothman, el principal socio en el informe de los Estados Unidos, Revista de Salud Pública y la Escuela Mailman.
Nami se encuentra ahora en los planes de acción nacionales o en el sitio de 5000 las empresas con más dinero, pero "las fuentes de financiación Ani" diversos capÃtulos del t. La organización tiene un producto o servicio polÃtico reconocido estrictas, dijo en su página web.
MARLBOROUGH, Mass.--( BUSINESS WIRE )--Advanced Cell Technology, Inc. ( OTCBB:ACTC ) reported that its hemangioblast-based technology can be used to generate functional platelets from human embryonic stem cells (hESCs). The research, which appears online (published-ahead-of- print) in Cell Research ' a Nature Group journal ' by scientists at ACT's joint venture "Stem Cell & Regenerative Medicine International" (SCRMI) and colleagues at Harvard Medical School, Cha University, and the University of Illinois, shows that it is feasible to generate functional megakaryocytes and platelets from hESCs on a large scale. The hESC-platelets displayed features that were indistinguishable from those of normal blood platelets, and participated in clot formation and retraction in vitro . High-speed video microscopy showed that the platelets contributed to thrombi after vascular injury in mice, providing the first evidence for in vivo functionality of hESC-derived platelets.
"However, once this technology is perfected, we believe pluripotent stem cells ' both embryonic and iPS cells ' will play an important role in developing a renewable, donorless source of transfusable platelets."
Platelets play a critical role in stimulating clot formation and repair of vascular injury. However, due to their short storage time, there is constant demand for this life-saving blood component. Low platelet levels can occur in patients for a variety of reasons, including trauma, chemotherapy, radiation treatment, or organ transplant surgery. To circumvent risks associated with these conditions, platelet transfusions have become a mainstay therapy; yet high demand and limited shelf life have created a constant shortage in transfusion supplies. The ability to generate HLA-matched platelets in vitro would provide significant advantages over currently used donor-dependent programs.
"Unlike other sources of platelets," said Robert Lanza, M.D., Chief Scientific Officer at ACT, and senior author of the study. "Human embryonic stem cells can be propagated indefinitely, providing a potentially unlimited and donorless source of cells for therapeutic purposes. This study shows that platelets can be produced from ES cells on a clinically relevant scale, and that they're functional upon transfusion into a living animal. The platelets displayed all of the structural and morphological criteria typical of blood platelets, and possessed characteristic properties of functional platelets such as activation by thrombin and formation of clots. Amazingly, they're even biconcave-shaped disks ' just like the real thing. Importantly, we demonstrated the platelets incorporated into thrombi (blood clots) in living mice in a manner similar to that observed for normal blood platelets. These results represent an important step towards generating an unlimited supply of platelets for transfusion. Since platelets contain no genetic material ' and can be irradiated before use ' they're ideal candidates for early clinical translation involving iPS cells."
High clinical demand for donated platelets has stimulated interest in generating renewable sources of transfusable platelets. This paper reports a method that is amenable to large scale production efforts. "The system is exponentially more efficient in generating megakaryocytes than previous methods," stated Shi-Jiang Lu, Ph.D., Senior Director of Stem International and co-senior author of the paper. "We have reduced dependence on animal serum and stroma, thus making the process more amenable to clinical translation. Thrombus formation in vivo is a rapid and highly dynamic process. It involves a large number of signaling pathways, enzymatic cascades, and the interplay of various protein components. By inducing natural platelet thrombus formation at the site of vascular injury in as little as 5-20 seconds, this system enabled us to monitor the real-time incorporation of the platelets into newly forming thrombi before they could be cleared from the microcirculation. We found that the hESC-derived platelets, like normal human blood platelets, incorporated into the developing mouse platelet thrombus through a platelet-specific mechanism."
"More research is clearly needed before this technology can advance into the clinic," stated Gary Rabin, Interim CEO and Chairman of ACT. "However, once this technology is perfected, we believe pluripotent stem cells ' both embryonic and iPS cells ' will play an important role in developing a renewable, donorless source of transfusable platelets."
Other researchers on the paper include Jaehyung Cho (co-senior author) and Eunsil Hahm from the University of Illinois at Chicago; Feng Li, Hong Yin, Qiang Feng, Erin Kimbrel, and Wei Wang from Stem Cell & Regenerative Medicine International (SCRMI); and Jonathan Thon and Joseph Italiano at Children's Hospital, Brigham and Women's Hospital/Harvard Medical School.
Advanced Cell Technology, Inc. is a biotechnology company applying cellular technology in the field of regenerative medicine. For more information, visit .
Forward-Looking Statements
Statements in this news release regarding future financial and operating results, future growth in research and development programs, potential applications of our technology, opportunities for the company and any other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not statements of historical fact (including statements containing the words "will," "believes," "plans," "anticipates," "expects," "estimates," and similar expressions) should also be considered to be forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward-looking statements, including: limited operating history, need for future capital, risks inherent in the development and commercialization of potential products, protection of our intellectual property, and economic conditions generally. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in the company's periodic reports, including the report on Form 10-K for the year ended December 31, 2009. Forward-looking statements are based on the beliefs, opinions, and expectations of the company's management at the time they are made, and the company does not assume any obligation to update its forward-looking statements if those beliefs, opinions, expectations, or other circumstances should change. Forward-looking statements are based on the beliefs, opinions, and expectations of the company's management at the time they are made, and the company does not assume any obligation to update its forward-looking statements if those beliefs, opinions, expectations, or other circumstances should change.
In the stem cell debate there has been a lot of heat generated, but not much light. Many claims and promises have been made, but most people, the public and the policymakers alike, do not know the whole truth about stem cell research and its cousin, cloning. THERE ARE ACTUALLY MANY sources of stem cells, yet most of the media attention has focused on embryonic stem cells. Embryonic stem cells from mice were first isolated in 1981, but the debate began in earnest in 1998 when human embryonic stem cells were first harvested. Embryonic stem cells come from early embryos within the first few days of life. At that stage of our life, about one week after conception, we resemble a hollow ball with some cells inside, a stage of our life called the “blastocyst.” It is at that point that we can implant into the wall of the uterus and start obtaining our nutrition from our mother’s womb. This is also the point at which scientists obtain embryonic stem cells.
Obtaining them requires breaking apart the embryo, resulting in his or her death. The cells are placed into a Petri dish, and the hope is that from the dish scientists can generate any tissue needed to repair damaged or diseased organs in the body. Despite the hype surrounding them, embryonic stem cells actually have little to offer for treatment of disease. Their supposed advantages—unlimited growth and potential for forming all tissues—are hindrances when it comes to transplants to repair damaged tissue. When transplanted into experimental animals, these cells generally continue this untamed behavior, with a tendency to form tumors or various unwanted tissues. A recent attempt to treat diabetes in mice using embryonic stem cells showed that the cells did not even form insulin-secreting cells, but they did form tumors.
Other experiments aimed at treating Parkinson’s disease in animals gave a slight improvement in some of the animals, but also killed 20% of the animals with brain tumors caused by the embryonic stem cells. The scientific literature is filled with similar results, even after more than 20 years of research with embryonic stem cells. Indeed, the National Institute of Health has noted that: “Thus, at this stage, any therapies based on the use of human ES cells are still hypothetical and highly experimental.” Cries for more human embryonic stem cell lines to be made available for federal funding are unjustified, as research on current lines shows insufficient evidence that they are either safe or effective. In terms of the science, proponents of embryonic stem cell research are playing on the emotions of the vulnerable—lacking facts and making empty promises about possible treatment of diseases. There is also the significant ethical question about embryonic stem cell research—should some human beings be sacrificed for the potential benefit of others? Embryonic stem cell research destroys the youngest, most vulnerable members of the species. We may not look now as we looked then, but we were all embryos at one time. If we had been used for research when we were embryos, we would not be here now to read these words. Is the remote possibility that medical treatments might arise worth the cost of cannibalizing other human beings? Similar promises are made about cloning. Cloning starts with creation of a new embryo. The process, termed “somatic cell nuclear transfer” or SCNT for short, involves removing the chromosomes from an egg cell, and transferring the chromosome-containing nucleus of a body cell (a somatic cell) into that egg cell.
What results is a new embryo, containing the genetic information of the person who supplied the body cell. All human cloning is reproductive. It creates—reproduces—a new developing human intended to be virtually identical to the person who was cloned. Both “reproductive cloning” and “therapeutic cloning” use exactly the same technique to create the clone. The clone is created as a new embryo and grown in the laboratory for several days. Then it is either implanted in the womb of a surrogate mother (“reproductive cloning”) or destroyed to harvest its embryonic stem cells for experiments (“therapeutic cloning”). It is the same embryo, but used for different purposes. In fact, the cloned embryo at that stage of development cannot be distinguished under the microscope from an embryo created by fertilization joining egg and sperm. And “therapeutic cloning” is obviously not therapeutic for the embryo—the new human is specifically created in order to be destroyed as a source of cells for experiments. Cloning research also poses a significant health threat to women. The process requires a tremendous number of human eggs to create a single clone, one scientist estimating that at least 100 eggs would be needed for each patient even if the process could ever be shown to work. A simple calculation reveals staggering numbers—to treat just the 17 million diabetes patients in the United States will require at least 1.7 billion human eggs, and approximately 85 million women to “donate” eggs.
The harvesting of eggs is not a simple process, like today’s plasma donation. It will subject huge numbers of women to health risks from high hormone doses and surgery required to harvest the eggs. The result will be that human eggs will become a commodity and disadvantaged women will be exploited on a global scale. The lack of success of cloning and embryonic stem cells should be compared with the real successes of adult stem cells. Adult stem cells are found not only in adults, but also in virtually every tissue of our body from birth onward, as well as in umbilical cord blood and placenta. Unlike destructive embryo research, harvesting these cells from patients does not harm the individual from whom they are obtained. Hundreds of scientific studies over the last few years document that adult stem cells are much more promising for repair of diseased tissue. Studies now indicate that some adult stem cells can form virtually all tissues of the body.
In a study published in May 2001, researchers found that one adult bone marrow stem cell could regenerate not only marrow and blood, but also form liver, lung, digestive tract, skin, heart, and muscle. Other researchers have found an enormous capacity to make new tissue in adult stem cells from various sources including bone marrow, peripheral blood, and umbilical cord blood. Even liposuctioned fat contains adult stem cells that can be transformed into other tissues. More importantly, adult stem cells have been shown repeatedly to be effective at treating disease. Studies in animals over the last several years have proven their ability to heal and repair damage from diseases such as diabetes, stroke, spinal cord injury, Parkinson’s disease, and retinal degeneration. But the biggest news, largely unreported, is that adult stem cells are already being used successfully to treat human patients. Thousands of patients have now benefited from adult stem cell treatments. These include reparative treatments with various cancers, autoimmune diseases such as multiple sclerosis, lupus, and arthritis, and anemias including sickle cell anemia. Adult stem cells are also being used to treat patients by formation of new cartilage, growing new corneas to restore sight to blind patients, potential treatments for stroke, and studies using adult stem cells have helped several hundred patients to repair damage after heart attacks. Early trials have shown initial success in treating patients for Parkinson’s disease and spinal cord injury. And, the first FDA approved trial to treat juvenile diabetes in human patients is ready to begin at Harvard Medical School, using adult cells.
An advantage of using adult stem cells is that in most cases the patient’s own stem cells can be used for the treatment, circumventing the problems of immune rejection, and adult stem cells do their repair work without causing tumor formation. These quiet successes, using the patient’s own adult stem cells, are advancing rapidly and producing the therapies about which embryonic stem cell advocates can only speculate. (An extensive list of the adult stem cell scientific literature can be found at appendix_k.html and stories of patients who have already been helped by adult stem cells are at cfm?i=IS04J01.)
We don’t yet understand how adult stem cells work their repair magic, but they continue to surprise even the scientists. As Robert Lanza, a proponent of embryonic stem cells and cloning has noted, “there is ample scientific evidence that adult stem cells can be used to repair damaged heart or brain tissue… if it works, it works, regardless of the mechanism.” That’s certainly the attitude of the patients who have experienced the real benefits of adult stem cells. Overwhelmingly the evidence reveals that it is adult stem cells that hold the promise of medical advancement, not the use of embryonic stem cells. Could there be more behind this debate than meets the eye? An attempt to view life within the first few days as a commodity, further moving us from a fixed reference point that all life, no matter if it is seven minutes old, seven months old or 70 years old, is still sacred as it reflects the Creator. To capitulate to the rhetoric and emotional appeal, which current science does not support, allowing seven day old embryos to be used for their cells today could lead to seven month old fetuses to be used for their parts tomorrow. The bottom line is this; the contrast between embryonic stem cells and adult stem cells is one of hype versus hope, empty promises versus real results. Adult stem cell research is daily proving itself capable of helping patients without moral and political difficulties.
If we are truly interested in providing treatments for suffering patients, we should rapidly pursue that which shows real promise without compromising the sanctity of human life. Tony Perkins is President of the Washington, D.C., based Family Research Council. Mr. Perkins is a former member of the Louisiana legislature where he served for eight years, and was recognized as a legislative pioneer for authoring measures like the nation’s first Covenant Marriage law. Under his leadership, FRC has worked to defend the Judeo-Christian values that this nation is founded upon. David A. Prentice, Ph.D., is Senior Fellow for Life Sciences at Family Research Council, and Affiliated Scholar for the Center for Clinical Bioethics, Georgetown University Medical Center.Online counseling is always available to help you out.
Dr. Prentice received his Ph.D. in Biochemistry from the University of Kansas, and was at Los Alamos National Laboratory and the University of Texas Medical School-Houston before joining Indiana State University, where he served as Acting Associate Dean of Arts and Sciences, Assistant Chair of Life Sciences, and was recognized with the University’s Distinguished Teaching Award and Distinguished Service Award. He is an internationally recognized expert on stem cell research and cloning, and has testified before the U.S. Congress, numerous state legislatures, the U.S. National Academy of Sciences, the Presidents Council on Bioethics, various international parliaments, and the United Nations.
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